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Gene CSF3R
Variant G644E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CSF3R G644E lies within the transmembrane domain of the Csf3r protein (UniProt.org). G644E is not transforming in cell culture (PMID: 29572350), but has not been biochemically characterized and therefore, its effect on Csf3r protein function is unknown.
Associated Drug Resistance
Category Variants Paths

CSF3R mutant CSF3R G644E

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Transcript NM_000760.4
gDNA chr1:g.36467585C>T
cDNA c.1931G>A
Protein p.G644E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011540749.1 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38
NM_156039.3 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38
XM_047446753.1 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38
NM_000760.4 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38
XM_005270493.1 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38
NM_172313.3 chr1:g.36467585C>T c.1931G>A p.G644E RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References