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Gene NTRK2
Variant F633L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NTRK2 F633L (corresponds to F617L in the canonical isoform) lies within the protein kinase domain of the Ntrk2 protein (UniProt.org). F633L has not been characterized in the scientific literature and therefore, its effect on Ntrk2 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

NTRK2 mutant NTRK2 F633L

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Transcript NM_006180.6
gDNA chr9:g.84948594T>C
cDNA c.1897T>C
Protein p.F633L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005252003.4 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
XM_047423432.1 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
XM_005252001.4 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
XM_017014751.3 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
XM_047423433.1 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
XM_005252004.3 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38
NM_006180.6 chr9:g.84948594T>C c.1897T>C p.F633L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References