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Gene | FBXW7 |
Variant | A481V |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FBXW7 A481V lies within WD repeat 3 of the Fbxw7 protein (UniProt.org). A481V has been identified in sequencing studies (PMID: 31754145), but has not been biochemically characterized and therefore, its effect on Fbxw7 protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FBXW7 mutant FBXW7 A481V |
Transcript | NM_033632.3 |
gDNA | chr4:g.152326208G>A |
cDNA | c.1442C>T |
Protein | p.A481V |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001349798.2 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_024454121.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_047415900.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_047415901.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532085 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_001013415 | chr4:g.152324243G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532083 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532085.3 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_001013415.1 | chr4:g.152324243G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532084.3 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_047415899.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_024454124.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_017008362 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_033632.3 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_047415897.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_033632.3 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_047415898.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_001349798.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_024454123.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_024454123.2 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532084 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532085.2 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_033632 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
NM_001013415.2 | chr4:g.152324243G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_011532084.2 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
XM_024454122.1 | chr4:g.152326208G>A | c.1442C>T | p.A481V | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
FBXW7 A481V | unknown |