Gene Variant Detail

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Gene SRC
Variant S225I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SRC S225I lies within the SH2 domain of the Src protein (UniProt.org). S225I has not been characterized in the scientific literature and therefore, its effect on Src protein function is unknown (PubMed, May 2020).
Associated Drug Resistance

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Transcript NM_198291
gDNA chr20:g.37396282G>T
cDNA c.674G>T
Protein p.S225I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017028026 chr20:g.37396263_37396264delTCinsAT c.673_674delTCinsAT p.S225I RefSeq GRCh38/hg38
XM_017028027 chr20:g.37396263_37396264delTCinsAT c.673_674delTCinsAT p.S225I RefSeq GRCh38/hg38
XM_017028025 chr20:g.37396263_37396264delTCinsAT c.673_674delTCinsAT p.S225I RefSeq GRCh38/hg38
XM_017028024 chr20:g.37396263_37396264delTCinsAT c.673_674delTCinsAT p.S225I RefSeq GRCh38/hg38
XM_011529013 chr20:g.37396282G>T c.674G>T p.S225I RefSeq GRCh38/hg38
NM_198291 chr20:g.37396282G>T c.674G>T p.S225I RefSeq GRCh38/hg38
NM_005417 chr20:g.37396282G>T c.674G>T p.S225I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Protein Effect Treatment Approaches
SRC S225I unknown