Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Gene Variant Descriptions||NOTCH1 C478S lies within the calcium-binding EGF-like domain 12 of the Notch1 protein (UniProt.org). C478S has been identified in the scientific literature (PMID: 27228302), but has not been biochemically characterized and therefore, its effect on Notch1 protein function is unknown (PubMed, Feb 2020).|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|