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Gene | FLT3 |
Variant | S71I |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 S71I lies within the extracellular domain of the Flt3 protein (UniProt.org). S71I has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 S71I |
Transcript | NM_004119.3 |
gDNA | chr13:g.28062023C>A |
cDNA | c.212G>T |
Protein | p.S71I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
XM_017020486 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
XM_017020489.1 | chr13:g.28048371_28048372delTCinsAT | c.211_212delTCinsAT | p.S71I | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
XM_017020486.1 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
XM_017020489 | chr13:g.28048371_28048372delGAinsAT | c.211_212delTCinsAT | p.S71I | RefSeq | GRCh38/hg38 |
XM_017020486.2 | chr13:g.28062023C>A | c.212G>T | p.S71I | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
FLT3 S71I | unknown |