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Gene | ATR |
Variant | D2331Y |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ATR D2331Y lies within the PI3K/PI4K domain of the Atr protein (UniProt.org). D2331Y has been identified in the scientific literature (PMID: 30957057, PMID: 29530932), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ATR mutant ATR D2331Y |
Transcript | NM_001184.4 |
gDNA | chr3:g.142465147C>A |
cDNA | c.6991G>T |
Protein | p.D2331Y |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001184 | chr3:g.142465147C>A | c.6991G>T | p.D2331Y | RefSeq | GRCh38/hg38 |
NM_001184.3 | chr3:g.142465147C>A | c.6991G>T | p.D2331Y | RefSeq | GRCh38/hg38 |
NM_001184.4 | chr3:g.142465147C>A | c.6991G>T | p.D2331Y | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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