Gene Variant Detail

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Gene HRAS
Variant R73H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS R73H does not lie within any known functional domains of the Hras protein (UniProt.org). R73H has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, May 2023).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS R73H

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Transcript NM_005343.4
gDNA chr11:g.533838C>T
cDNA c.218G>A
Protein p.R73H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005343 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_001130442 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_176795 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38
NM_176795.5 chr11:g.533838C>T c.218G>A p.R73H RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References