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Gene ARID1A
Variant R2158fs
Impact List frameshift
Protein Effect unknown
Gene Variant Descriptions ARID1A R2158fs results in a change in the amino acid sequence of the Arid1a protein beginning at aa 2158 of 2285, likely resulting in premature truncation of the functional protein (UniProt.org). R2158fs has not been characterized in the scientific literature and therefore, its effect on Arid1a protein function is unknown (PubMed, Jan 2024).
Associated Drug Resistance
Category Variants Paths

ARID1A mutant ARID1A R2158fs

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Transcript NM_006015.6
gDNA chr1:g.(26780369_26780370)
cDNA c.(6472_6471)
Protein p.R2158fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006015 chr1:g.(26780369_26780370) c.(6472_6471) p.R2158fs RefSeq GRCh38/hg38
NM_006015.5 chr1:g.(26780369_26780370) c.(6472_6471) p.R2158fs RefSeq GRCh38/hg38
NM_006015.6 chr1:g.(26780369_26780370) c.(6472_6471) p.R2158fs RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References