Profile Response Detail

Molecular Profile Unknown unknown
Therapy Citarinostat + Paclitaxel
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By cstatz
Update By cstatz


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable Citarinostat + Paclitaxel Preclinical - Cell line xenograft Actionable In a preclinical study, the combination of ACY-241 and Taxol (paclitaxel) resulted in increased efficacy in advanced solid tumor xenograft models, including pancreatic and ovarian (AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4822). detail...
PubMed Id Reference Title Details
Abstract 4822: Combination efficacy of the selective HDAC inhibitor ACY-241 and paclitaxel in solid tumor models Full reference...