Profile Response Detail

Molecular Profile MET positive
Therapy Emibetuzumab
Indication/Tumor Type Advanced Solid Tumor
Response Type sensitive
Create By tyin
Update By tyin


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
MET positive Advanced Solid Tumor sensitive Emibetuzumab Phase I Actionable In a Phase I trial, Emibetuzumab (LY2875358) treatment resulted in durable partial response in 4% (1/23) of Met-positive patients with advanced solid tumors (J Clin Oncol 31, 2013 (suppl; abstr 8093)). detail...
PubMed Id Reference Title Details
First-in-human dose escalation study of LY2875358 (LY), a bivalent MET antibody, as monotherapy and in combination with erlotinib (E) in patients with advanced cancer. Full reference...