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Molecular Profile Unknown unknown
Therapy Nivolumab
Indication/Tumor Type transitional cell carcinoma
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown transitional cell carcinoma not applicable Nivolumab FDA approved Actionable In a Phase II trial (CheckMate 275) that supported FDA approval, treatment with Opdivo (nivolumab) resulted in objective response in 19.6% (52/265) of urothelial carcinoma patients with prior platinum therapy, with complete response in 2% (6/265), and partial response in 17% (46/265) of patients (PMID: 28131785; NCT02387996). detail... 28131785
PubMed Id Reference Title Details
(28131785) Nivolumab in metastatic urothelial carcinoma after platinum therapy (CheckMate 275): a multicentre, single-arm, phase 2 trial. Full reference...
Opdivo (nivolumab) FDA Drug Label Full reference...