Profile Response Detail

Molecular Profile Unknown unknown
Therapy E7046
Indication/Tumor Type colon cancer
Response Type not applicable
Create By cstatz
Update By cstatz

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colon cancer not applicable E7046 Preclinical Actionable In a preclinical study, a colon cancer mouse model harboring an APC mutation demonstrated decreased polyp formation and decreased cell proliferation when treated with the EP4 antagonist, E7046 (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr B198). detail...
PubMed Id Reference Title Details
Abstract B198: Pharmacological profile of the PGE2 EP4 receptor antagonist E7046 Full reference...