Profile Response Detail

Molecular Profile KRAS mutant
Therapy OPB-111077
Indication/Tumor Type colon cancer
Response Type predicted - sensitive
Create By cstatz
Update By djd

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
KRAS mutant colon cancer predicted - sensitive OPB-111077 Phase I Actionable In a Phase I trial, a patient with colon cancer harboring a KRAS mutation demonstrated stable disease when treated with OPB-111077 (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr B118). detail...
PubMed Id Reference Title Details
Abstract B118: A phase 1, open-label multiple dose escalation trial to determine safety and tolerability of once daily OPB-111077 in subjects with advanced cancer Full reference...