Molecular Profile | KRAS mutant |
Therapy | OPB-111077 |
Indication/Tumor Type | colon cancer |
Response Type | predicted - sensitive |
Create By | cstatz |
Update By | djd |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References | KRAS mutant | colon cancer | predicted - sensitive | OPB-111077 | Phase I | Actionable | In a Phase I trial, a patient with colon cancer harboring a KRAS mutation demonstrated stable disease when treated with OPB-111077 (Mol Cancer Ther 2015;14(12 Suppl 2):Abstract nr B118). | detail... |
---|
PubMed Id | Reference Title | Details |
---|---|---|
Abstract B118: A phase 1, open-label multiple dose escalation trial to determine safety and tolerability of once daily OPB-111077 in subjects with advanced cancer | Full reference... |