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Molecular Profile Unknown unknown
Therapy Oxaliplatin + Resminostat
Indication/Tumor Type colorectal cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable Oxaliplatin + Resminostat Preclinical - Cell line xenograft Actionable In a preclinical study, the combination of Resminostat (4SC-201) and Eloxatin (oxaliplatin) induced apoptosis in a colorectal cancer (CRC) cell line and primary colon cancer cells in culture, and inhibited tumor growth in a CRC cell line xenograft model, with increased activity compared to either agent alone (PMID: 26831668). 26831668
PubMed Id Reference Title Details
(26831668) Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells. Full reference...