Profile Response Detail

Molecular Profile Unknown unknown
Therapy PR610
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable
Create By rliu
Update By smockus


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable PR610 Preclinical Actionable In a preclinical study, PR610 inhibited EGFR auto-phosphorylation and downstream signaling, and induced cell-cycle arrest and an anti-proliferative response in human cancer cell lines in culture (Mol Cancer Ther 2013;12(11 Suppl):B278). detail...
PubMed Id Reference Title Details
PR610: A novel hypoxia-selective tyrosine kinase inhibitor in phase I clinical trial. Full reference...