Profile Response Detail

Molecular Profile Unknown unknown
Therapy CCT241533 + Rucaparib
Indication/Tumor Type colorectal cancer
Response Type not applicable
Create By cstatz
Update By cstatz

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable CCT241533 + Rucaparib Preclinical - Cell culture Actionable In a preclinical study, CCT241533 enhanced the growth inhibition effect of Rubraca (rucaparib) in colorectal cancer cells in culture (PMID: 21239475). 21239475
PubMed Id Reference Title Details
(21239475) CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Full reference...