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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|SETBP1 mutant||chronic myelomonocytic leukemia||not applicable||N/A||Clinical Study||Prognostic||In clinical analyses, mutations in SETBP1 were associated with poor prognosis in patients with chronic myelomonocytic leukemia (PMID: 29225884, PMID: 28158286, PMID: 28209919, PMID: 23558523, PMID: 23832012).||29225884 28209919 23832012 23558523 28158286|
|PubMed Id||Reference Title||Details|
|(23832012)||Somatic SETBP1 mutations in myeloid malignancies.||Full reference...|
|(28158286)||Prognostic significance of SETBP1 mutations in myelodysplastic syndromes, chronic myelomonocytic leukemia, and chronic neutrophilic leukemia: A meta-analysis.||Full reference...|
|(23558523)||SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia: independent prognostic impact in CMML.||Full reference...|
|(28209919)||Clinical significance of CSF3R, SRSF2 and SETBP1 mutations in chronic neutrophilic leukemia and chronic myelomonocytic leukemia.||Full reference...|
|(29225884)||SETBP1 mutations as a biomarker for myelodysplasia /myeloproliferative neoplasm overlap syndrome.||Full reference...|