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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Unknown unknown||lung non-small cell carcinoma||not applicable||Pegilodecakin + Pembrolizumab||Phase I||Actionable||In a Phase Ib trial (IVY), Pegilodecakin (AM0010) and Keytruda (pembrolizumab) (n=5) or Opdivo (nivolumab) (n=29) combination therapy demonstrated safety and preliminary efficacy, resulting in an objective response rate of 43% (12/28, 1 complete response, 11 partial responses) and a disease control rate of 82% (23/28) in evaluable patients with non-small cell lung carcinoma, with a median duration of response of 10.3 months (PMID: 31563517; NCT02009449).||31563517|