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Request curation for specific Genes, variants, or PubMed publications.
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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BRAF L597S||melanoma||sensitive||TAK-733||Phase I||Actionable||In a Phase I trial, one metastatic melanoma patient carrying a BRAF L597S mutation, had a partial response to the MEK inhibitor, TAK-733 (PMID: 22798288).||22798288|