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Molecular Profile Unknown unknown
Therapy Trifluridine-tipiracil hydrochloride
Indication/Tumor Type gastroesophageal junction adenocarcinoma
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown gastroesophageal junction adenocarcinoma not applicable Trifluridine-tipiracil hydrochloride FDA approved Actionable In a Phase III trial (TAGS) that supproted FDA approval, Lonsurf (trifluridine/tipiracil hydrochloride) treatment resulted in improved overall survival (5.7 vs 3.6 months, HR=0.69, p=0.00029) compared to placebo in patients with heavily pretreated metastatic or advanced gastric cancer or gastroesophageal junction adenocarcinoma (PMID: 30355453; NCT02500043). detail... 30355453
PubMed Id Reference Title Details
(30355453) Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial. Full reference...
Lonsurf (trifluridine/tipiracil hydrochloride) FDA Drug Label Full reference...