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Molecular Profile BRAF wild-type ERBB2 amp NRAS wild-type
Therapy Lapatinib + Trastuzumab
Indication/Tumor Type rectum cancer
Response Type sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF wild-type ERBB2 amp NRAS wild-type rectum cancer sensitive Lapatinib + Trastuzumab Guideline Actionable Herceptin (trastuzumab) in combination with Tykerb (lapatinib) is included in guidelines as second-line therapy for advanced or metastatic rectum cancer patients with ERBB2 amplification and wild-type NRAS and BRAF ( detail...
PubMed Id Reference Title Details Full reference...