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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|BRAF wild-type ERBB2 amp NRAS wild-type||rectum cancer||sensitive||Lapatinib + Trastuzumab||Guideline||Actionable||Herceptin (trastuzumab) in combination with Tykerb (lapatinib) is included in guidelines as second-line therapy for advanced or metastatic rectum cancer patients with ERBB2 amplification and wild-type NRAS and BRAF (NCCN.org).||detail...|
|PubMed Id||Reference Title||Details|