Profile Response Detail

Molecular Profile ERBB2 negative
Therapy Docetaxel + Ramucirumab
Indication/Tumor Type Her2-receptor negative breast cancer
Response Type no benefit
Create By stafford
Update By tyin


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ERBB2 negative Her2-receptor negative breast cancer no benefit Docetaxel + Ramucirumab Phase III Actionable In a Phase III trial, Cyramze (ramucirumab) in combination with Taxotere (docetaxel) did not improve clinical outcomes in ERBB2 (HER2)-negative breast cancer patients (PMID: 25185099). 25185099
PubMed Id Reference Title Details
(25185099) Primary results of ROSE/TRIO-12, a randomized placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer. Full reference...