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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|CSF3R T618I CSF3R Q741*||hematologic cancer||predicted - resistant||Ruxolitinib||Preclinical - Cell culture||Actionable||In a preclinical study, transformed hematologic cells co-expressing CSF3R T618I and CSF3R Q741* were resistant to treatment with Jakafi (ruxolitinib) in culture (PMID: 28031554).||28031554|