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Molecular Profile ERBB2 R188C
Therapy Canertinib
Indication/Tumor Type cancer
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ERBB2 R188C cancer sensitive Canertinib Preclinical - Cell culture Actionable In a preclinical study, Canertinib (CI-1033) inhibited growth of transformed cells expressing ERBB2 (HER2) R188C in culture (PMID: 32366937). 32366937
PubMed Id Reference Title Details
(32366937) ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia. Full reference...