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Molecular Profile Unknown unknown
Therapy BO-112
Indication/Tumor Type melanoma
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown melanoma not applicable BO-112 Preclinical - Patient cell culture Actionable In a preclinical study, BO-112 treatment inhibited cell viability and induced apoptosis in mouse melanoma cells, and induced cytotoxicity and increased apoptosis in cells derived from metastatic lesions of melanoma patients in culture, and intratumoral delivery of BO-112 enhanced infiltration of T-lymphocytes, reduced tumor growth, and delayed progression in syngeneic mouse models (PMID: 31046839). 31046839
PubMed Id Reference Title Details
(31046839) Immunotherapeutic effects of intratumoral nanoplexed poly I:C. Full reference...