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Molecular Profile Unknown unknown
Therapy M7824
Indication/Tumor Type biliary tract cancer
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown biliary tract cancer not applicable M7824 Phase I Actionable In a Phase I trial, Bintrafusp alfa (M7824) treatment in patients with advanced biliary tract cancer resulted in an objective response rate of 20% (6/30), including two complete responses and four partial responses, and led to an additional six patients demonstrating stable disease, and median progression-free survival of 2.5 months, and median overall survival of 12.7 months (PMID: 32461347; NCT02699515). 32461347
PubMed Id Reference Title Details
(32461347) Phase I study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with pretreated biliary tract cancer. Full reference...