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Molecular Profile PIK3CA act mut
Therapy Dactolisib
Indication/Tumor Type ovarian clear cell adenocarcinoma
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
PIK3CA act mut ovarian clear cell adenocarcinoma sensitive Dactolisib Preclinical Actionable In a preclinical study, BEZ235 demonstrated efficacy in mouse xenograft models of ovarian clear cell adenocarcinoma with PIK3CA mutations (PMID: 24927217). 24927217
PubMed Id Reference Title Details
(24927217) The PI3K/mTOR dual inhibitor NVP-BEZ235 reduces the growth of ovarian clear cell carcinoma. Full reference...