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Molecular Profile CSF3R N579Y
Therapy Ruxolitinib
Indication/Tumor Type hematologic cancer
Response Type predicted - sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
CSF3R N579Y hematologic cancer predicted - sensitive Ruxolitinib Preclinical - Cell culture Actionable In a preclinical study, Jakafi (ruxolitinib) treatment inhibited colony formation and decreased viability of transformed cells expressing CSF3R N579Y in culture (Blood (2021), 138 (Supplement 1): 3582). detail...
PubMed Id Reference Title Details
A Novel CSF3R Activating Mutation Identified in a Patient with Chronic Neutrophilic Leukemia Full reference...