Profile Response Detail


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Molecular Profile ALK rearrange
Therapy Alectinib + Irinotecan
Indication/Tumor Type lung small cell carcinoma
Response Type predicted - sensitive


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ALK rearrange lung small cell carcinoma predicted - sensitive Alectinib + Irinotecan Case Reports/Case Series Actionable In a clinical case study, treatment with the combination of Alecensa (alectinib) and Camptosar (irinotecan) resulted in a partial response with progression-free survival lasting longer than 6 months in a small cell lung carcinoma patient harboring an ALK rearrangement (PMID: 34729013). 34729013
PubMed Id Reference Title Details
(34729013) ALK Rearrangement in Small-Cell Lung Cancer and Durable Response to Alectinib: A Case Report. Full reference...