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Molecular Profile | RAD51C del |
Therapy | AZD5305 |
Indication/Tumor Type | ovarian cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
RAD51C del | ovarian cancer | sensitive | AZD5305 | Preclinical - Cell culture | Actionable | In a preclinical study, AZD5305 inhibited colony formation in an ovarian cancer cell line with RAD51C deletion in culture (PMID: 35929986). | 35929986 |
PubMed Id | Reference Title | Details |
---|---|---|
(35929986) | Preclinical characterization of AZD5305, a next generation, highly selective PARP1 inhibitor and trapper. | Full reference... |