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|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|CTNNB1 S33F||hepatocellular carcinoma||sensitive||WNTinib||Preclinical - Patient cell culture||Actionable||In a preclinical study, WNTinib inhibited Ezh2 phosphorylation and viability in a patient-derived hepatocellular carcinoma cell line harboring CTNNB1 S33F in 2D and 3D culture (PMID: 37537299).||37537299|