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Molecular Profile | FGFR3 - BAIAP2L1 |
Therapy | ASP5878 |
Indication/Tumor Type | urinary bladder cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR3 - BAIAP2L1 | urinary bladder cancer | sensitive | ASP5878 | Preclinical - Cell culture | Actionable | In a preclinical study, ASP5878 treatment inhibited proliferation of a bladder cancer cell line harboring an FGFR3-BAIAP2L1 fusion in culture (Mol Cancer Ther December 2015 14; A170). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
Preclinical antitumor activity of ASP5878, a novel inhibitor of FGFR1, 2, 3 and 4, in bladder cancer harboring FGFR3-fusion or -mutation | Full reference... |