Profile Response Detail

Molecular Profile Unknown unknown
Therapy Aldoxorubicin + Buparlisib
Indication/Tumor Type leiomyosarcoma
Response Type not applicable
Create By cstatz
Update By cstatz


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown leiomyosarcoma not applicable Aldoxorubicin + Buparlisib Preclinical Actionable In a preclinical study, the combination of BKM120 and doxorubicin produced an additive effect when treating leiomyosarcoma cells (PMID: 26952093). 26952093
PubMed Id Reference Title Details
(26952093) PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma. Full reference...