Profile Response Detail

Molecular Profile Unknown unknown
Therapy trifluridine/tipiracil hydrochloride
Indication/Tumor Type colorectal cancer
Response Type not applicable
Create By tyin
Update By smockus

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable trifluridine/tipiracil hydrochloride FDA approved Actionable In a Phase III trial supporting FDA approval, Lonsurf (trifluridine/tipiracil hydrochloride) demonstrated improved median overall survival (7.1 vs 5.3 months), median progression free survival (2.0 vs 1.7 months), and 32% reduction of death risk compared to placebo in treatment-refractory metastatic colorectal cancer patients (PMID: 27126991). 27126991 detail...
PubMed Id Reference Title Details
(27126991) TAS-102 for Treatment of Advanced Colorectal Cancers That Are No Longer Responding to Other Therapies. Full reference...
Lonsurf (trifluridine/tipiracil hydrochloride) FDA Drug Label Full reference...