Profile Response Detail

Molecular Profile Unknown unknown
Therapy Vantictumab + Paclitaxel
Indication/Tumor Type Her2-receptor negative breast cancer
Response Type not applicable
Create By spatt
Update By spatt

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Her2-receptor negative breast cancer not applicable Vantictumab + Paclitaxel Phase Ib/II Actionable In a Phase Ib trial, the combination of Vantictumab (OMP-18R5) and Taxol (paclitaxel) was well-tolerated and demonstrated preliminary efficacy in patients with metastatic HER2-negative breast cancer (J Clin Oncol 34, 2016 (suppl; abstr 2516)). detail...
PubMed Id Reference Title Details
Phase 1b study of WNT inhibitor vantictumab (VAN, human monoclonal antibody) with Paclitaxel (P) in patients (pts) with 1st- to 3rd-line metastatic HER2-negative breast cancer (BC). Full reference...