Profile Response Detail


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Molecular Profile Unknown unknown
Therapy Ruxolitinib
Indication/Tumor Type myelodysplastic/myeloproliferative neoplasm
Response Type not applicable


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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown myelodysplastic/myeloproliferative neoplasm not applicable Ruxolitinib Phase I Actionable In a Phase I trial, Jakafi (ruxolitinib) treatment demonstrated safety and preliminary efficacy in chronic myelomonocytic leukemia patients, resulted in a total response rate of 35% (7/20) and reduction of Stat5 signaling (PMID: 26858309). 26858309
PubMed Id Reference Title Details
(26858309) A Multi-Institution Phase I Trial of Ruxolitinib in Patients with Chronic Myelomonocytic Leukemia (CMML). Full reference...