Profile Response Detail

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Molecular Profile Unknown unknown
Therapy JQ1
Indication/Tumor Type triple-receptor negative breast cancer
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown triple-receptor negative breast cancer not applicable JQ1 Preclinical - Cell line xenograft Actionable In a preclinical study, triple-receptor negative breast cancer cells demonstrated sensitivity to treatment with JQ1, resulting in decrease cell proliferation and cell cycle arrest in culture and tumor growth inhibition in cell line xenograft models (PMID: 27256375). 27256375
PubMed Id Reference Title Details
(27256375) In Silico Analysis Guides Selection of BET Inhibitors for Triple-Negative Breast Cancer Treatment. Full reference...