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Molecular Profile | Unknown unknown |
Therapy | JQ1 |
Indication/Tumor Type | triple-receptor negative breast cancer |
Response Type | not applicable |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
Unknown unknown | triple-receptor negative breast cancer | not applicable | JQ1 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, triple-receptor negative breast cancer cells demonstrated sensitivity to treatment with JQ1, resulting in decrease cell proliferation and cell cycle arrest in culture and tumor growth inhibition in cell line xenograft models (PMID: 27256375). | 27256375 |
PubMed Id | Reference Title | Details |
---|---|---|
(27256375) | In Silico Analysis Guides Selection of BET Inhibitors for Triple-Negative Breast Cancer Treatment. | Full reference... |