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Molecular Profile Unknown unknown
Therapy Adavosertib + Cisplatin
Indication/Tumor Type Advanced Solid Tumor
Response Type not applicable

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown Advanced Solid Tumor not applicable Adavosertib + Cisplatin Phase I Actionable In a Phase I trial, the combination of Adavosertib (MK-1775) and Platinol (cisplatin) resulted in a partial response in 15.5% (9/58) of patients and stable disease in 40% (23/58) of patients, all with advanced solid tumors (PMID: 27601554). 27601554
PubMed Id Reference Title Details
(27601554) Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors. Full reference...