Profile Treatment Approach Detail

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Profile Treatment Approach Name RET Inhibitor
Profile Name RET act mut
Drug Class RET Inhibitor 39
Therapy

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PubMed Id Reference Title Details
(22146228) Multi-targeted tyrosine kinase inhibitors in clinical development: focus on XL-184 (cabozantinib). Full reference...
(24705026) Mechanisms of RET signaling in cancer: current and future implications for targeted therapy. Full reference...
(21551259) In vitro transforming potential, intracellular signaling properties, and sensitivity to a kinase inhibitor (sorafenib) of RET proto-oncogene variants Glu511Lys, Ser649Leu, and Arg886Trp. Full reference...