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Ref Type
Authors Marlene Hennessy, Souri Felix, Andrew Wahba, Saul Kivimae, Takahiko Miyama, Mariella Cabrera, Maria Gabriela Segura, Jonathan Zalevsky, Willem Overwijk, Nancy Gordon
Title A potential immunotherapeutic approach for the treatment of osteosarcoma
Journal AACR Annual Meeting 2019 Online Proceedings
Abstract Text AACR Annual Meeting 2019, Abstract 3210


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown osteosarcoma not applicable NKTR-214 Preclinical Actionable In a preclinical study, NKTR-214 treatment inhibited growth of primary tumor, regrowth after amputation, and lung metastasis in disseminated and orthotopic mouse models of osteosarcoma (AACR Annual Meeting 2019, Abstract 3210). detail...