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Ref Type
PMID
Authors Sreerupa Valli Challa, Shenghua Zhou, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Rayomand Gimi, Diane Schmidt, Dillon Cleary, Nezam Afdhal, Radhakrishnan Iyer
Title Preclinical studies of SB 11285, a novel STING agonist for immuno-oncology.
URL https://ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_suppl.e14616
Abstract Text Journal of Clinical Oncology 35, no. 15_suppl

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
SB 11285 SB 11285 0 1
Drug Name Trade Name Synonyms Drug Classes Drug Description
SB 11285 SB11285|SB-11285 STING1 Agonist 19 SB 11285 is an agonist of Stimulator of Interferon Genes (STING1), which potentially activates immune cells resulting in anti-tumor immunity (Journal of Clinical Oncology 2017 35:15_suppl, e14616, PMID: 31355488).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References