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Ref Type
PMID
Authors P.R. Clingan, A.M. Mant, G.E. Richardson, D.M. Kowalski, P. Koralewski, I. Lugowska, A. Dechaphunkul, C. Charoentum, A. Sookprasert, V. Sriuranpong, A. Akopov, V. Kozlov, N. Fadeeva, B. Kasparov, N.V. Kovalenko, V. Oschepkov, L. Gorelik, Y. Kunes, J. Oliviero , D.L. Harris
Title Safety, efficacy, and pharmacokinetic (PK) profile of cosibelimab, an anti‐PD‐L1 antibody, in patients (pts) with advanced cancers
Journal Vol Issue Date Pages Journal Short Title
URL https://www.annalsofoncology.org/article/S0923-7534(19)58691-4/pdf
Abstract Text Ann Oncol. Oct 2019, Vol 30 (Suppl_5): v177

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Cosibelimab Cosibelimab 0 2
Drug Name Trade Name Synonyms Drug Classes Drug Description
Cosibelimab CK-301|CK 301|TG-1501|TG1501|TG 1501 Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117 Cosibelimab (CK-301) is a human monoclonal antibody against PD-L1 (CD274), which may block immune checkpoint, lead to anti-tumor immune response (Ann Oncol. Oct 2019, Vol 30 (Suppl_5): v177).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References