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Ref Type
PMID
Authors Eskouhie Tchaparian
Title The antitumor activity of hyaluronic acid nimuselide-NH2 bioconjugate (CA102N) in human colorectal cancer (CRC)
URL https://cancerres.aacrjournals.org/content/75/15_Supplement/4471
Abstract Text Cancer Res 2015;75(15 Suppl):Abstract nr 4471

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
CA102N CA102N 0 1
Drug Name Trade Name Synonyms Drug Classes Drug Description
CA102N CA 102N|CA-102N|Nim-HA Conjugate|HA-Nimesulide CA102N is composed of sodium hyaluronate (NaHA) in conjugation with the COX-2 inhibitor nimesulide, which may target the HA receptor CD44-expressing tumor cells for growth inhibition (Cancer Res 2015;75(15 Suppl):Abstract nr 4471, PMID: 28392690).
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References