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Ref Type
PMID
Authors Hee Kyu Lee, Hong Woo Kim, Ho-Juhn Song, Jaekyoo Lee, In Yong Lee, Youngsam Kim and Jong Sung Koh
Title A novel selective inhibitor of FLT3 kinase as a therapeutics for AML.
Journal
Vol
Issue
Date
URL https://mct.aacrjournals.org/content/10/11_Supplement/C196
Abstract Text Mol Cancer Ther 2011;10(11 Suppl):Abstract nr C196

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Gene Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown acute myeloid leukemia not applicable SKI-G-801 Preclinical - Cell line xenograft Actionable In a preclinical study, SKI-G-801 treatment induced tumor regression in a cell line xenograft model of acute myeloid leukemia (Mol Cancer Ther 2011;10(11 Suppl):Abstract nr C196). detail...