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PMID | |
Authors | R. B. Corcoran, C. E. Atreya, G. S. Falchook, J. R. Infante, O. Hamid, W. A. Messersmith, A. Daud, E. L. Kwak, D. Ryan, R. Kurzrock, P. Sun, E. A. Cunningham, K. W. Orford, M. Motwani, Y. Bai, K .Patel, A. P. Venook, S. Kopetz |
Title | Phase 1-2 trial of the BRAF inhibitor dabrafenib (D) plus MEK inhibitor trametinib (T) in BRAF V600 mutant colorectal cancer (CRC): Updated efficacy and biomarker analysis. |
Journal | J Clin Oncol |
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URL | http://meetinglibrary.asco.org/content/131743-144 |
Abstract Text | J Clin Oncol 32:5s, 2014 (suppl; abstr 3517) |
Molecular Profile | Treatment Approach |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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