Reference Detail

Ref Type
PMID
Authors E. Calvo, M. Gil Martín, A. Cubillo, J. Machiels, S. Rottey, F. Mardjuadi, K. Geboes, R. Salazar, J. Beadle, C. Ellis, K. Fisher and C. Blanc
Title A PHASE 1 STUDY OF ENADENOTUCIREV, AN ONCOLYTIC AD11/AD3 CHIMERIC GROUP B ADENOVIRUS, ADMINISTERED INTRAVENOUSLY - ANALYSIS OF DOSE EXPANSION AND REPEAT CYCLE COHORTS IN PATIENTS WITH METASTATIC COLORECTAL CANCER (MCRC)
Journal Ann Oncol
Vol
Issue
Date
URL http://annonc.oxfordjournals.org/content/25/suppl_4/iv367.1.abstract
Abstract Text Ann Oncol (2014) 25 (suppl 4): iv367.

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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown colorectal cancer not applicable Enadenotucirev Phase I Actionable In a Phase I trial, Enadenotucirev demonstrated safety and uptake by tumor cells in metastatic colorectal cancer patients (Ann Oncol (2014) 25 (suppl 4): iv367). detail...