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Authors | Byoung Heon Kang | ||||||||||||
Title | Novel in vivo pan-Hsp90 family protein inhibitor, Panvotinib-401, showed potent anticancer activities without HSF1 activation | ||||||||||||
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URL | http://www.abstractsonline.com/Plan/ViewAbstract.aspx?mID=4017&sKey=d0cbfd99-0744-49e4-a827-562c416014d8&cKey=5b87c7e4-79ec-456c-9ca0-037f038f5114&mKey=1d10d749-4b6a-4ab3-bcd4-f80fb1922267 | ||||||||||||
Abstract Text |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Panvotinib-401 | Panvotinib-401 | 0 | 0 |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Panvotinib-401 | HSP90 Inhibitor 35 | Panvotinib-401 is a small molecule Hsp90 inhibitor that is mitochondrial inner membrane-permeable, resulting in cancer cell toxicity (AACR, Cancer Res: April 2016; Volume 57, Abstract #3896). |
Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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