Reference Detail

Ref Type
Authors Ravaud, R.J. Motzer, H.S. Pandha, M. Staehler, D. George, A.J. Pantuck, A. Patel, Y-H. Chang, B. Escudier, F. Donskov, A. Magheli, G. Carteni, B. Laguerre, P. Tomczak, J. Breza, P. Gerletti, X. Lin, M. Lechuga, J-F. Martini, J-J. Patard
Title Phase III trial of sunitinib (SU) vs placebo (PBO) as adjuvant treatment for high-risk renal cell carcinoma (RCC) after nephrectomy (S-TRAC)
Abstract Text ESMO 2016 Congress in Copenhagen, Abstract LBA11_PR


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Molecular Profile Treatment Approach
Gene Name Source Synonyms Protein Domains Gene Description Gene Role
Therapy Name Drugs Efficacy Evidence Clinical Trials
Drug Name Trade Name Synonyms Drug Classes Drug Description
Variant Impact Protein Effect Variant Description Associated with drug Resistance
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown renal cell carcinoma not applicable Sunitinib Phase III Actionable In a Phase III clinical trial, treatment with Sutent (sunitinib) resulted in prolonged disease free survival (HR = 0.761) compared to placebo in post-nephrectomy patients with renal cell carcinoma (ESMO 2016 Congress in Copenhagen, Abstract LBA11_PR). detail...