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Authors | R. S. Kristeleit, G. Shapiro, P. LoRusso, J.R. Infante, M.Flynn, M. R. Patel, S. M. Tolaney, J. F. Hilton, A. H. Calvert, H.i Giordano, J. D. Isaacson, J. Borrow, A. R. Allen, S. S. Jaw-Tsai, Howard A. Burris | ||||||||||||
Title | A phase I dose-escalation and PK study of continuous oral rucaparib in patients with advanced solid tumors. | ||||||||||||
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URL | http://meetinglibrary.asco.org/content/115538-132 | ||||||||||||
Abstract Text | J Clin Oncol 31, 2013 (suppl; abstr 2585) |
Molecular Profile | Treatment Approach |
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Gene Name | Source | Synonyms | Protein Domains | Gene Description | Gene Role |
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Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
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Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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Gene | Variant | Impact | Protein Effect | Variant Description | Associated with drug Resistance |
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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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